One-pot three-condensation synthesis of 12-aryl-tetrahydrobenzo[α]xanthene- 11-one derivatives catalyzed by Manganese (IV) oxide as an efficient, mild and inexpensive catalyst under solvent-free conditions was studied. The method presented is a safe and eco-friendly approach for the multi-component synthesis of xanthene derivatives with many merits in comparison with other reported results including short reaction times, solvent-free conditions, good to high yields, facile reaction profiles and easy work up.
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